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Whole-genome doubling confers unique genetic vulnerabilities on tumour cells.
Quinton, Ryan J; DiDomizio, Amanda; Vittoria, Marc A; Kotýnková, Kristýna; Ticas, Carlos J; Patel, Sheena; Koga, Yusuke; Vakhshoorzadeh, Jasmine; Hermance, Nicole; Kuroda, Taruho S; Parulekar, Neha; Taylor, Alison M; Manning, Amity L; Campbell, Joshua D; Ganem, Neil J.
Afiliación
  • Quinton RJ; Department of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
  • DiDomizio A; Department of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
  • Vittoria MA; Department of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
  • Kotýnková K; Department of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
  • Ticas CJ; Department of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
  • Patel S; Department of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
  • Koga Y; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Vakhshoorzadeh J; Department of Pharmacology & Experimental Therapeutics, Boston University School of Medicine, Boston, MA, USA.
  • Hermance N; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, USA.
  • Kuroda TS; Department of Molecular Pathobiology and Cell Adhesion Biology, Mie University Graduate School of Medicine, Mie, Japan.
  • Parulekar N; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Taylor AM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Manning AL; Cancer Program, Broad Institute, Cambridge, MA, USA.
  • Campbell JD; Department of Pathology and Cell Biology, Columbia University Medical Center, Member, Herbert Irving Comprehensive Cancer Center, New York, NY, USA.
  • Ganem NJ; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, USA.
Nature ; 590(7846): 492-497, 2021 02.
Article en En | MEDLINE | ID: mdl-33505027
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Genoma Humano / Tetraploidía / Mitosis / Neoplasias Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Genoma Humano / Tetraploidía / Mitosis / Neoplasias Tipo de estudio: Prognostic_studies Límite: Female / Humans / Male Idioma: En Revista: Nature Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos