Quantitative assessment of glioblastoma phenotypes in vitro establishes cell migration as a robust readout of Crk and CrkL activity.

Park, Taeju; Large, Neka; Curran, Tom

Quantitative assessment of glioblastoma phenotypes in vitro establishes cell migration as a robust readout of Crk and CrkL activity.

Park, Taeju; Large, Neka; Curran, Tom.

Afiliación

Park T; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, Missouri, USA; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA. Electronic address: tjpark@cmh.edu.
Large N; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Curran T; Children's Mercy Research Institute, Children's Mercy Kansas City, Kansas City, Missouri, USA; Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA.

J Biol Chem ; 296: 100390, 2021.

Article en En | MEDLINE | ID: mdl-33561443

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/metabolismo; Glioblastoma/metabolismo; Glioblastoma/patología; Proteínas Proto-Oncogénicas c-crk/metabolismo; Proteínas Adaptadoras Transductoras de Señales/genética; Línea Celular Tumoral; Movimiento Celular/fisiología; Proliferación Celular/fisiología; Técnicas de Silenciamiento del Gen; Glioblastoma/genética; Humanos; Técnicas In Vitro; Fenotipo; Proteínas Proto-Oncogénicas c-crk/genética

Palabras clave

Crk; CrkL; cell adhesion; cell invasion; cell migration; cell proliferation; gene knockdown; glioblastoma

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Glioblastoma / Proteínas Adaptadoras Transductoras de Señales / Proteínas Proto-Oncogénicas c-crk Límite: Humans Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article

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