Impact of Colon Cancer Location on the Prognostic Significance of Nutritional Indexes and Inflammatory Markers.
In Vivo
; 35(2): 1261-1269, 2021.
Article
en En
| MEDLINE
| ID: mdl-33622929
ABSTRACT
BACKGROUND/AIM:
The prognosis of colorectal cancer is reported to differ depending on the tumor site, and clinical differences depending on the site of occurrence have gained attention. The aim was to compare nutrition index and inflammatory markers according to the site of colon cancer. PATIENTS ANDMETHODS:
We retrospectively analyzed 272 cases of stage I-III colon cancer (55% males, 45% females). The clinical characteristics, nutrition index and inflammatory markers were compared between patients with right colon cancer (RCC, n=119) and those with left colon cancer (LCC, n=153), and the relapse-free survival was then compared.RESULTS:
RCC was associated with older age (p=0.03), female gender (p=0.003), higher T stage (p=0.01), elevated platelet/lymphocyte ratio (PLR) (p=0.009), and elevated CONUT score (p=0.028). The prognostic values differed between RCC and LCC (RCC CONUT score, p=0.04, LCC PLR, p=0.02).CONCLUSION:
RCC was associated with an elevated CONUT score and PLR. In RCC, the CONUT score was an independent recurrence factor, and in LCC, the PLR was an independent recurrence factor.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Evaluación Nutricional
/
Neoplasias del Colon
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
In Vivo
Asunto de la revista:
NEOPLASIAS
Año:
2021
Tipo del documento:
Article