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Effect of Postreinduction Therapy Consolidation With Blinatumomab vs Chemotherapy on Disease-Free Survival in Children, Adolescents, and Young Adults With First Relapse of B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial.
Brown, Patrick A; Ji, Lingyun; Xu, Xinxin; Devidas, Meenakshi; Hogan, Laura E; Borowitz, Michael J; Raetz, Elizabeth A; Zugmaier, Gerhard; Sharon, Elad; Bernhardt, Melanie B; Terezakis, Stephanie A; Gore, Lia; Whitlock, James A; Pulsipher, Michael A; Hunger, Stephen P; Loh, Mignon L.
Afiliación
  • Brown PA; Departments of Oncology and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Ji L; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles.
  • Xu X; Children's Oncology Group, Monrovia, California.
  • Devidas M; Department of Global Pediatric Medicine, St Jude Children's Research Hospital, Memphis, Tennessee.
  • Hogan LE; Department of Pediatrics, Stony Brook Children's, Stony Brook, New York.
  • Borowitz MJ; Departments of Pathology and Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
  • Raetz EA; Department of Pediatrics, NYU Langone Health, New York, New York.
  • Zugmaier G; Amgen Research (Munich), GmbH, Munich, Germany.
  • Sharon E; Division of Cancer Treatment and Diagnosis, National Cancer Institute, Cancer Therapy Evaluation Program, Bethesda, Maryland.
  • Bernhardt MB; Section of Hematology/Oncology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
  • Terezakis SA; University of Minnesota, Department of Radiation Oncology, Minneapolis.
  • Gore L; University of Colorado School of Medicine and Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora.
  • Whitlock JA; Hospital for Sick Children and University of Toronto, Toronto, Canada.
  • Pulsipher MA; Transplantation and Cellular Therapy, Children's Hospital Los Angeles Cancer and Blood Diseases Institute, Los Angeles, California.
  • Hunger SP; Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and The Perelman School of Medicine at The University of Pennsylvania, Philadelphia.
  • Loh ML; Department of Pediatrics, Benioff Children's Hospital and the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco.
JAMA ; 325(9): 833-842, 2021 03 02.
Article en En | MEDLINE | ID: mdl-33651090

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Leucemia de Células B / Protocolos de Quimioterapia Combinada Antineoplásica / Anticuerpos Biespecíficos / Trasplante de Células Madre Hematopoyéticas / Leucemia-Linfoma Linfoblástico de Células Precursoras / Inmunoterapia / Antineoplásicos Tipo de estudio: Clinical_trials / Guideline Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: JAMA Año: 2021 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Leucemia de Células B / Protocolos de Quimioterapia Combinada Antineoplásica / Anticuerpos Biespecíficos / Trasplante de Células Madre Hematopoyéticas / Leucemia-Linfoma Linfoblástico de Células Precursoras / Inmunoterapia / Antineoplásicos Tipo de estudio: Clinical_trials / Guideline Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: JAMA Año: 2021 Tipo del documento: Article