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Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors.
Phillips, Darren C; Buchanan, Fritz G; Cheng, Dong; Solomon, Larry R; Xiao, Yu; Xue, John; Tahir, Stephen K; Smith, Morey L; Zhang, Haichao; Widomski, Deborah; Abraham, Vivek C; Xu, Nan; Liu, Zhihong; Zhou, Li; DiGiammarino, Enrico; Lu, Xin; Rudra-Ganguly, Nandini; Trela, Bruce; Morgan-Lappe, Susan E.
Afiliación
  • Phillips DC; Oncology Discovery, AbbVie Inc., North Chicago, Illinois. darren.phillips@abbvie.com susan.morgan-lappe@abbvie.com.
  • Buchanan FG; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Cheng D; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Solomon LR; AbbVie Inc., North Chicago, Illinois.
  • Xiao Y; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Xue J; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Tahir SK; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Smith ML; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Zhang H; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Widomski D; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Abraham VC; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Xu N; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Liu Z; Oncology Discovery, AbbVie Inc., North Chicago, Illinois.
  • Zhou L; Protein Biochemistry, AbbVie Inc., North Chicago, Illinois.
  • DiGiammarino E; Protein Biochemistry, AbbVie Inc., North Chicago, Illinois.
  • Lu X; Genomic Research Center, AbbVie Inc., North Chicago, Illinois.
  • Rudra-Ganguly N; Drug Metabolism and Pharmacokinetics, AbbVie Inc., North Chicago, Illinois.
  • Trela B; Pre-clinical Safety, AbbVie Inc., North Chicago, Illinois.
  • Morgan-Lappe SE; Oncology Discovery, AbbVie Inc., North Chicago, Illinois. darren.phillips@abbvie.com susan.morgan-lappe@abbvie.com.
Cancer Res ; 81(12): 3402-3414, 2021 06 15.
Article en En | MEDLINE | ID: mdl-33687950
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas Recombinantes de Fusión / Factor IX / Fragmentos Fc de Inmunoglobulinas / Neoplasias Colorrectales / Ligando Inductor de Apoptosis Relacionado con TNF / Receptores del Ligando Inductor de Apoptosis Relacionado con TNF Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas Recombinantes de Fusión / Factor IX / Fragmentos Fc de Inmunoglobulinas / Neoplasias Colorrectales / Ligando Inductor de Apoptosis Relacionado con TNF / Receptores del Ligando Inductor de Apoptosis Relacionado con TNF Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2021 Tipo del documento: Article