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Phase 2 study of TAS-117, an allosteric akt inhibitor in advanced solid tumors harboring phosphatidylinositol 3-kinase/v-akt murine thymoma viral oncogene homolog gene mutations.
Lee, Jii Bum; Jung, Minkyu; Beom, Seung Hoon; Kim, Gun Min; Kim, Hye Ryun; Choi, Hye Jin; Sohn, Joo Hyuk; Ahn, Joong Bae; Rha, Sun Young; Chung, Hyun Cheol.
Afiliación
  • Lee JB; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.
  • Jung M; Song-Dang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Korea.
  • Beom SH; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.
  • Kim GM; Song-Dang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Korea.
  • Kim HR; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.
  • Choi HJ; Song-Dang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Korea.
  • Sohn JH; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.
  • Ahn JB; Song-Dang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Korea.
  • Rha SY; Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.
  • Chung HC; Song-Dang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, Korea.
Invest New Drugs ; 39(5): 1366-1374, 2021 10.
Article en En | MEDLINE | ID: mdl-33723724
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Proteínas Proto-Oncogénicas c-akt / Compuestos Heterocíclicos con 3 Anillos / Neoplasias Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fosfatidilinositol 3-Quinasas / Proteínas Proto-Oncogénicas c-akt / Compuestos Heterocíclicos con 3 Anillos / Neoplasias Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Invest New Drugs Año: 2021 Tipo del documento: Article