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The CD33 short isoform is a gain-of-function variant that enhances Aß1-42 phagocytosis in microglia.
Bhattacherjee, Abhishek; Jung, Jaesoo; Zia, Sameera; Ho, Madelene; Eskandari-Sedighi, Ghazaleh; St Laurent, Chris D; McCord, Kelli A; Bains, Arjun; Sidhu, Gaurav; Sarkar, Susmita; Plemel, Jason R; Macauley, Matthew S.
Afiliación
  • Bhattacherjee A; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • Jung J; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • Zia S; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, T6G 2E1, Canada.
  • Ho M; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, T6G 2E1, Canada.
  • Eskandari-Sedighi G; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • St Laurent CD; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • McCord KA; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • Bains A; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • Sidhu G; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • Sarkar S; Department of Chemistry, University of Alberta, 11227 Saskatchewan Dr., Gunning Lemieux Chemistry Centre E5-18A, Edmonton, T6G 2G2, Canada.
  • Plemel JR; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, T6G 2E1, Canada.
  • Macauley MS; Department of Medicine, Division of Neurology, University of Alberta, Edmonton, T6G 2E1, Canada.
Mol Neurodegener ; 16(1): 19, 2021 03 25.
Article en En | MEDLINE | ID: mdl-33766097
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Fagocitosis / Péptidos beta-Amiloides / Microglía / Lectina 3 Similar a Ig de Unión al Ácido Siálico Límite: Animals / Female / Humans / Male Idioma: En Revista: Mol Neurodegener Año: 2021 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Fagocitosis / Péptidos beta-Amiloides / Microglía / Lectina 3 Similar a Ig de Unión al Ácido Siálico Límite: Animals / Female / Humans / Male Idioma: En Revista: Mol Neurodegener Año: 2021 Tipo del documento: Article País de afiliación: Canadá