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Photochemical Probe Identification of a Small-Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)*.
Lanyon-Hogg, Thomas; Ritzefeld, Markus; Zhang, Leran; Andrei, Sebastian A; Pogranyi, Balazs; Mondal, Milon; Sefer, Lea; Johnston, Callum D; Coupland, Claire E; Greenfield, Jake L; Newington, Joshua; Fuchter, Matthew J; Magee, Anthony I; Siebold, Christian; Tate, Edward W.
Afiliación
  • Lanyon-Hogg T; Department of Pharmacology, University of Oxford, Oxford, OX1 3QT, UK.
  • Ritzefeld M; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Zhang L; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Andrei SA; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Pogranyi B; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Mondal M; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Sefer L; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Johnston CD; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Coupland CE; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Greenfield JL; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Newington J; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Fuchter MJ; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
  • Magee AI; National Heart & Lung Institute, Imperial College London, London, SW7 2AZ, UK.
  • Siebold C; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
  • Tate EW; Department of Chemistry, Imperial College London, London, W12 0BZ, UK.
Angew Chem Int Ed Engl ; 60(24): 13542-13547, 2021 06 07.
Article en En | MEDLINE | ID: mdl-33768725
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Acetiltransferasas / Marcadores de Afinidad / Bibliotecas de Moléculas Pequeñas Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Acetiltransferasas / Marcadores de Afinidad / Bibliotecas de Moléculas Pequeñas Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido