Alternative exon splicing and differential expression in pancreatic islets reveals candidate genes and pathways implicated in early diabetes development.

Rehman, Sayeed Ur; Schallschmidt, Tanja; Rasche, Axel; Knebel, Birgit; Stermann, Torben; Altenhofen, Delsi; Herwig, Ralf; Schürmann, Annette; Chadt, Alexandra; Al-Hasani, Hadi

Rehman, Sayeed Ur; Schallschmidt, Tanja; Rasche, Axel; Knebel, Birgit; Stermann, Torben; Altenhofen, Delsi; Herwig, Ralf; Schürmann, Annette; Chadt, Alexandra; Al-Hasani, Hadi.

Afiliación

Rehman SU; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Medical Faculty, Duesseldorf, Germany.
Schallschmidt T; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Rasche A; Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, New Delhi, 110062, India.
Knebel B; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Medical Faculty, Duesseldorf, Germany.
Stermann T; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Altenhofen D; Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Herwig R; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Medical Faculty, Duesseldorf, Germany.
Schürmann A; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Chadt A; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research at Heinrich Heine University, Medical Faculty, Duesseldorf, Germany.
Al-Hasani H; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.

Mamm Genome ; 32(3): 153-172, 2021 06.

Article en En | MEDLINE | ID: mdl-33880624

Asunto(s)

Diabetes Mellitus Tipo 2/genética; Galectina 2/genética; Insulina/genética; PPAR gamma/genética; Adipogénesis/genética; Empalme Alternativo/genética; Animales; Glucemia/genética; Antígenos CD36/genética; Diabetes Mellitus Tipo 2/patología; Exones/genética; Regulación de la Expresión Génica/genética; Humanos; Células Secretoras de Insulina/metabolismo; Células Secretoras de Insulina/patología; Islotes Pancreáticos/crecimiento & desarrollo; Islotes Pancreáticos/patología; Redes y Vías Metabólicas/genética; Ratones; Sitios de Carácter Cuantitativo/genética; Retinal-Deshidrogenasa/genética; Transcriptoma/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Galectina 2 / PPAR gamma / Diabetes Mellitus Tipo 2 / Insulina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Mamm Genome Asunto de la revista: GENETICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania

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