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Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children.
Ramaswamy, Anjali; Brodsky, Nina N; Sumida, Tomokazu S; Comi, Michela; Asashima, Hiromitsu; Hoehn, Kenneth B; Li, Ningshan; Liu, Yunqing; Shah, Aagam; Ravindra, Neal G; Bishai, Jason; Khan, Alamzeb; Lau, William; Sellers, Brian; Bansal, Neha; Guerrerio, Pamela; Unterman, Avraham; Habet, Victoria; Rice, Andrew J; Catanzaro, Jason; Chandnani, Harsha; Lopez, Merrick; Kaminski, Naftali; Dela Cruz, Charles S; Tsang, John S; Wang, Zuoheng; Yan, Xiting; Kleinstein, Steven H; van Dijk, David; Pierce, Richard W; Hafler, David A; Lucas, Carrie L.
Afiliación
  • Ramaswamy A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA.
  • Brodsky NN; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Sumida TS; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA; Department of Neurology, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Comi M; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA; Department of Neurology, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Asashima H; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA; Department of Neurology, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Hoehn KB; Department of Pathology, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Li N; Department of Biostatistics, Yale School of Public Health, New Haven, CT, 06520, USA.
  • Liu Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT, 06520, USA.
  • Shah A; Department of Internal Medicine (Cardiology), Yale University School of Medicine, New Haven, CT, 06510, USA; Department of Computer Science, Yale University, New Haven, CT, 06520, USA.
  • Ravindra NG; Department of Internal Medicine (Cardiology), Yale University School of Medicine, New Haven, CT, 06510, USA; Department of Computer Science, Yale University, New Haven, CT, 06520, USA.
  • Bishai J; Department of Internal Medicine (Cardiology), Yale University School of Medicine, New Haven, CT, 06510, USA; Department of Computer Science, Yale University, New Haven, CT, 06520, USA.
  • Khan A; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Lau W; NIH Center for Human Immunology (CHI), NIAID, NIH, Bethesda, MD, 20892, USA; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, 20892, USA.
  • Sellers B; NIH Center for Human Immunology (CHI), NIAID, NIH, Bethesda, MD, 20892, USA.
  • Bansal N; NIH Center for Human Immunology (CHI), NIAID, NIH, Bethesda, MD, 20892, USA; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, 20892, USA.
  • Guerrerio P; Food Allergy Research Section, Laboratory of Allergic Diseases, NIAID, NIH, Bethesda, MD, 20892, USA.
  • Unterman A; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New, Haven, CT, 06520, USA.
  • Habet V; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Rice AJ; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA.
  • Catanzaro J; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Chandnani H; Department of Pediatrics, Loma Linda School of Medicine, Loma Linda, CA, 92354, USA.
  • Lopez M; Department of Pediatrics, Loma Linda School of Medicine, Loma Linda, CA, 92354, USA.
  • Kaminski N; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New, Haven, CT, 06520, USA.
  • Dela Cruz CS; Section of Pulmonary, Critical Care and Sleep Medicine, Yale University School of Medicine, New, Haven, CT, 06520, USA.
  • Tsang JS; NIH Center for Human Immunology (CHI), NIAID, NIH, Bethesda, MD, 20892, USA; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, 20892, USA.
  • Wang Z; Department of Biostatistics, Yale School of Public Health, New Haven, CT, 06520, USA.
  • Yan X; Department of Biostatistics, Yale School of Public Health, New Haven, CT, 06520, USA; Department of Computer Science, Yale University, New Haven, CT, 06520, USA.
  • Kleinstein SH; Department of Pathology, Yale University School of Medicine, New Haven, CT, 06520, USA; Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06511, USA.
  • van Dijk D; Department of Internal Medicine (Cardiology), Yale University School of Medicine, New Haven, CT, 06510, USA; Department of Computer Science, Yale University, New Haven, CT, 06520, USA.
  • Pierce RW; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Hafler DA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA; Department of Neurology, Yale University School of Medicine, New Haven, CT, 06520, USA.
  • Lucas CL; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, 06519, USA. Electronic address: carrie.lucas@yale.edu.
Immunity ; 54(5): 1083-1095.e7, 2021 05 11.
Article en En | MEDLINE | ID: mdl-33891889
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Síndrome de Respuesta Inflamatoria Sistémica / SARS-CoV-2 / COVID-19 Tipo de estudio: Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Síndrome de Respuesta Inflamatoria Sistémica / SARS-CoV-2 / COVID-19 Tipo de estudio: Risk_factors_studies Límite: Adolescent / Child / Child, preschool / Humans Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos