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CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells.
Kluesner, Mitchell G; Lahr, Walker S; Lonetree, Cara-Lin; Smeester, Branden A; Qiu, Xiaohong; Slipek, Nicholas J; Claudio Vázquez, Patricia N; Pitzen, Samuel P; Pomeroy, Emily J; Vignes, Madison J; Lee, Samantha C; Bingea, Samuel P; Andrew, Aneesha A; Webber, Beau R; Moriarity, Branden S.
Afiliación
  • Kluesner MG; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
  • Lahr WS; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Lonetree CL; Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Smeester BA; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA.
  • Qiu X; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
  • Slipek NJ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Claudio Vázquez PN; Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Pitzen SP; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA.
  • Pomeroy EJ; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
  • Vignes MJ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Lee SC; Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA.
  • Bingea SP; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA.
  • Andrew AA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
  • Webber BR; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.
  • Moriarity BS; Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA.
Nat Commun ; 12(1): 2437, 2021 04 23.
Article en En | MEDLINE | ID: mdl-33893286
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Adenosina / Biología Computacional / Citidina / Sistemas CRISPR-Cas / Edición Génica Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Adenosina / Biología Computacional / Citidina / Sistemas CRISPR-Cas / Edición Génica Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos