A prometastatic splicing program regulated by SNRPA1 interactions with structured RNA elements.

Fish, Lisa; Khoroshkin, Matvei; Navickas, Albertas; Garcia, Kristle; Culbertson, Bruce; Hänisch, Benjamin; Zhang, Steven; Nguyen, Hoang C B; Soto, Larisa M; Dermit, Maria; Mardakheh, Faraz K; Molina, Henrik; Alarcón, Claudio; Najafabadi, Hamed S; Goodarzi, Hani

Fish, Lisa; Khoroshkin, Matvei; Navickas, Albertas; Garcia, Kristle; Culbertson, Bruce; Hänisch, Benjamin; Zhang, Steven; Nguyen, Hoang C B; Soto, Larisa M; Dermit, Maria; Mardakheh, Faraz K; Molina, Henrik; Alarcón, Claudio; Najafabadi, Hamed S; Goodarzi, Hani.

Afiliación

Fish L; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
Khoroshkin M; Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA.
Navickas A; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
Garcia K; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA.
Culbertson B; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
Hänisch B; Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA.
Zhang S; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
Nguyen HCB; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA.
Soto LM; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
Dermit M; Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA.
Mardakheh FK; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
Molina H; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA 94158, USA.
Alarcón C; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.
Najafabadi HS; Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA.
Goodarzi H; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.

Science ; 372(6543)2021 05 14.

Article en En | MEDLINE | ID: mdl-33986153

Asunto(s)

Empalme Alternativo; Neoplasias de la Mama/patología; Metástasis de la Neoplasia/genética; ARN/genética; ARN/metabolismo; Ribonucleoproteína Nuclear Pequeña U2/metabolismo; Proteínas Adaptadoras Transductoras de Señales/genética; Algoritmos; Animales; Sitios de Unión; Neoplasias de la Mama/genética; Línea Celular Tumoral; Progresión de la Enfermedad; Exones; Técnicas de Silenciamiento del Gen; Humanos; Neoplasias Pulmonares/secundario; Ratones; Ratones Endogámicos NOD; Ratones SCID; Invasividad Neoplásica; Trasplante de Neoplasias; Conformación de Ácido Nucleico; Plectina/genética; Unión Proteica; Interferencia de ARN; ARN Nuclear Pequeño/química; ARN Nuclear Pequeño/metabolismo; RNA-Seq; Ribonucleoproteína Nuclear Pequeña U2/genética; Programas Informáticos; Empalmosomas/metabolismo; Proteínas Supresoras de Tumor/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / ARN / Ribonucleoproteína Nuclear Pequeña U2 / Empalme Alternativo / Metástasis de la Neoplasia Límite: Animals / Humans Idioma: En Revista: Science Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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