GPCRs: The most promiscuous druggable receptor of the mankind.

Alhosaini, Khaled; Azhar, Asim; Alonazi, Asma; Al-Zoghaibi, F

Alhosaini, Khaled; Azhar, Asim; Alonazi, Asma; Al-Zoghaibi, F.

Afiliación

Alhosaini K; Department of Pharmacology & Toxicology, College of Pharmacy, King Saud University, Post Box 2457, Riyadh 11451, Saudi Arabia.
Azhar A; Interdisciplinary Biotechnology Unit, AMU Aligarh, UP, India.
Alonazi A; Department of Pharmacology & Toxicology, College of Pharmacy, King Saud University, Post Box 2457, Riyadh 11451, Saudi Arabia.
Al-Zoghaibi F; Molecular BioMedicine Program, Research Centre, King Faisal Specialist Hospital and Research Centre, P.O.Box: 3354, MBC:03, Riyadh 11211, Saudi Arabia.

Saudi Pharm J ; 29(6): 539-551, 2021 Jun.

Article en En | MEDLINE | ID: mdl-34194261

Palabras clave

AC, Adenylyl Cyclase; Arrestin; CCR, Chemokine Receptor; COX, Cyclooxygenase; DAG, Diacylglycerol; Drugs; ERK, Extracellular signal-Regulated Kinase; G proteins; GIP, Gastric Inhibitory Peptide; GLP1R, Glucagon-Like Peptide-1 Receptor; GPCR; GRKs; GRKs, G protein-coupled Receptor Kinases; Heterodimerization; IP3, Inositol 1,4,5-triphosphate; MAPK, Mitogen-Activated Protein Kinase; NMDA, N-Methyl D-Aspartate; Nbs, Nanobodies; PAR-1, Protease Activated Receptor 1; PIP2, Phosphatidylinositol-4,5-bisphosphate; PKA, Protein Kinase A; Signaling; cAMP, cyclic AMP

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Saudi Pharm J Año: 2021 Tipo del documento: Article País de afiliación: Arabia Saudita

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Saudi Pharm J Año: 2021 Tipo del documento: Article País de afiliación: Arabia Saudita