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Silver, copper and copper oxide nanoparticles in the fight against human viruses: progress and perspectives.
Tortella, G R; Pieretti, J C; Rubilar, O; Fernández-Baldo, M; Benavides-Mendoza, A; Diez, M C; Seabra, A B.
Afiliación
  • Tortella GR; Centro de Excelencia en Investigación Biotecnológica Aplicada al Medio Ambiente, CIBAMA-BIOREN, Universidad de La Frontera, Temuco, Chile.
  • Pieretti JC; Center for Natural and Human Sciences, Universidade Federal do ABC (UFABC), Santo André, Brazil.
  • Rubilar O; Chemical Engineering Department, Universidad de La Frontera, Temuco, Chile.
  • Fernández-Baldo M; National Scientific and Technical Research Council | Conicet · INQUISAL Instituto de Química San Luis, Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, San Luis, Argentina.
  • Benavides-Mendoza A; Departamento de Horticultura, Universidad Autónoma Agraria Antonio Narro, Saltillo, Mexico.
  • Diez MC; Centro de Excelencia en Investigación Biotecnológica Aplicada al Medio Ambiente, CIBAMA-BIOREN, Universidad de La Frontera, Temuco, Chile.
  • Seabra AB; Center for Natural and Human Sciences, Universidade Federal do ABC (UFABC), Santo André, Brazil.
Crit Rev Biotechnol ; 42(3): 431-449, 2022 May.
Article en En | MEDLINE | ID: mdl-34233551
The rapid development of nanomedicine has created a high demand for silver, copper and copper oxide nanoparticles. Due to their high reactivity and potent antimicrobial activity, silver and copper-based nanomaterials have been playing an important role in the search for new alternatives for the treatment of several issues of concern, such as pathologies caused by bacteria and viruses. Viral diseases are a significant and constant threat to public health. The most recent example is the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this context, the object of the present review is to highlight recent progress in the biomedical uses of these metal nanoparticles for the treatment and prevention of human viral infections. We discuss the antiviral activity of AgNPs and Cu-based NPs, including their actions against SARS-CoV-2. We also discuss the toxicity, biodistribution and excretion of AgNPs and CuNPs, along with their uses in medical devices or on inert surfaces to avoid viral dissemination by fomites. The challenges and limitations of the biomedical use of these nanoparticles are presented.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Nanopartículas del Metal / Tratamiento Farmacológico de COVID-19 Límite: Humans Idioma: En Revista: Crit Rev Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Chile

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Nanopartículas del Metal / Tratamiento Farmacológico de COVID-19 Límite: Humans Idioma: En Revista: Crit Rev Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Chile