Cryptoyunnanones A-H, Complex Flavanones from Cryptocarya yunnanensis.
J Nat Prod
; 84(8): 2209-2216, 2021 08 27.
Article
en En
| MEDLINE
| ID: mdl-34282909
ABSTRACT
Eight new complex flavanones with a novel linkage, cryptoyunnanones A-H (1-8), together with four known α-pyrones, were isolated from the leaves and twigs of Cryptocarya yunnanensis. The structures of 1-8 including their absolute configurations were characterized by spectroscopic data analysis and single-crystal X-ray crystallography. Plausible biosynthetic pathways for the formation of compounds 1-8 were proposed. Compounds 1-4 exhibited cytotoxicity against HCT-116, MDA-MB-231, and PC-3 cancer cells with IC50 values from 6.4 to 9.1 µM.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Cryptocarya
/
Flavanonas
/
Antineoplásicos Fitogénicos
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Nat Prod
Año:
2021
Tipo del documento:
Article