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Protease inhibitor-based direct-acting antivirals are associated with increased risk of aminotransferase elevations but not hepatic dysfunction or decompensation.
Torgersen, Jessie; Newcomb, Craig W; Carbonari, Dena M; Rentsch, Christopher T; Park, Lesley S; Mezochow, Alyssa; Mehta, Rajni L; Buchwalder, Lynn; Tate, Janet P; Bräu, Norbert; Bhattacharya, Debika; Lim, Joseph K; Taddei, Tamar H; Justice, Amy C; Lo Re, Vincent.
Afiliación
  • Torgersen J; Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Biostatistics, Epidemiology, and Informatics, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Traini
  • Newcomb CW; Department of Biostatistics, Epidemiology, and Informatics, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Carbonari DM; Department of Biostatistics, Epidemiology, and Informatics, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Rentsch CT; Department of Non-communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; VA Connecticut Healthcare System, West Haven, CT, USA.
  • Park LS; Stanford Center for Population Health Sciences, Stanford University School of Medicine, Stanford, CA, USA.
  • Mezochow A; Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Mehta RL; VA Connecticut Healthcare System, West Haven, CT, USA; Department of Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Buchwalder L; VA Connecticut Healthcare System, West Haven, CT, USA; Department of Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Tate JP; VA Connecticut Healthcare System, West Haven, CT, USA; Department of Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Bräu N; James J. Peters VA Medical Center, Bronx, NY, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Bhattacharya D; VA Greater Los Angeles Healthcare System and David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Lim JK; VA Connecticut Healthcare System, West Haven, CT, USA; Department of Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Taddei TH; VA Connecticut Healthcare System, West Haven, CT, USA; Department of Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Justice AC; VA Connecticut Healthcare System, West Haven, CT, USA; Department of Medicine, Yale School of Medicine, New Haven, CT, USA; Division of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA.
  • Lo Re V; Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Biostatistics, Epidemiology, and Informatics, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Traini
J Hepatol ; 75(6): 1312-1322, 2021 12.
Article en En | MEDLINE | ID: mdl-34333102
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Antivirales / Inhibidores de Proteasas / Fallo Hepático Agudo / Transaminasas Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Antivirales / Inhibidores de Proteasas / Fallo Hepático Agudo / Transaminasas Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged País/Región como asunto: America do norte Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2021 Tipo del documento: Article