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Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K carrier protein from Neisseria meningitidis.
González, Luis Javier; Encinosa Guzmán, Pedro E; Machado, Wendy; Pousa, Satomy; Leyva, Alejandro; Arguelles, Ana Laura Cano; Cabrera, Gleysin; Espinosa, Luis Ariel; Parra, Rubén; Hernández, Rachel; Soto, Yamil Bello; Ledesma, Frank L; Joglar, Marisdania; Guirola, Osmany; Kurt, Louise Ulrich; Carvalho, Paulo C; Cabrales, Ania; Garay, Hilda; Besada, Vladimir; Durán, Rosario; Takao, Toshifumi; Estrada, Mario Pablo; Rodríguez-Mallon, Alina.
Afiliación
  • González LJ; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba. luis.javier@cigb.edu.cu.
  • Encinosa Guzmán PE; Animal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Machado W; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Pousa S; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Leyva A; , Unidad de Bioquímica y Proteómica Analítica (UByPA), Institut Pasteur de Montevideo, Mataojo 2020, Montevideo, Uruguay.
  • Arguelles ALC; Instituto de Investigaciones Biológicas Clemente Estable (IIBCE), 11600, Montevideo, Uruguay.
  • Cabrera G; Animal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Espinosa LA; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Parra R; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Hernández R; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Soto YB; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Ledesma FL; Animal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Joglar M; Animal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Guirola O; Animal Biotechnology Department, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Kurt LU; Bioinformatics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Carvalho PC; Laboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Fiocruz, Rua Professor Algacyr Munhoz Mader, 3775, Ciudade Industrial de Curitiba, Curitiba, Paraná, 81310-020, Brazil.
  • Cabrales A; Laboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Fiocruz, Rua Professor Algacyr Munhoz Mader, 3775, Ciudade Industrial de Curitiba, Curitiba, Paraná, 81310-020, Brazil.
  • Garay H; Synthetic Peptides Laboratory, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Besada V; Synthetic Peptides Laboratory, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Durán R; Department of Proteomics, Center for Genetic Engineering and Biotechnology (CIGB), Avenida 31, e/ 158 y 190, Cubanacán, Playa, 10600, Havana, Cuba.
  • Takao T; , Unidad de Bioquímica y Proteómica Analítica (UByPA), Institut Pasteur de Montevideo, Mataojo 2020, Montevideo, Uruguay.
  • Estrada MP; Instituto de Investigaciones Biológicas Clemente Estable (IIBCE), 11600, Montevideo, Uruguay.
  • Rodríguez-Mallon A; Institute for Protein Research, Osaka University, Suita Campus, Osaka, 565, Japan.
Anal Bioanal Chem ; 413(23): 5885-5900, 2021 Sep.
Article en En | MEDLINE | ID: mdl-34341841
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Garrapatas / Proteínas de la Membrana Bacteriana Externa / Vacunas / Cromatografía Liquida / Espectrometría de Masas en Tándem / Neisseria meningitidis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Anal Bioanal Chem Año: 2021 Tipo del documento: Article País de afiliación: Cuba
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Garrapatas / Proteínas de la Membrana Bacteriana Externa / Vacunas / Cromatografía Liquida / Espectrometría de Masas en Tándem / Neisseria meningitidis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Anal Bioanal Chem Año: 2021 Tipo del documento: Article País de afiliación: Cuba