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Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen.
Giubilaro, Jenna; Schuetz, Doris A; Stepniewski, Tomasz M; Namkung, Yoon; Khoury, Etienne; Lara-Márquez, Mónica; Campbell, Shirley; Beautrait, Alexandre; Armando, Sylvain; Radresa, Olivier; Duchaine, Jean; Lamarche-Vane, Nathalie; Claing, Audrey; Selent, Jana; Bouvier, Michel; Marinier, Anne; Laporte, Stéphane A.
Afiliación
  • Giubilaro J; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, Canada.
  • Schuetz DA; Research Institute of the McGill University Health Center (RI-MUHC), Montreal, QC, Canada.
  • Stepniewski TM; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, QC, Canada.
  • Namkung Y; Research Programme on Biomedical Informatics (GRIB), Department of Experimental and Health Sciences of Pompeu, Fabra University (UPF)-Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
  • Khoury E; InterAx Biotech AG, Villigen, Switzerland.
  • Lara-Márquez M; Research Institute of the McGill University Health Center (RI-MUHC), Montreal, QC, Canada.
  • Campbell S; Department of Medicine, Research Institute of the McGill University Health Center (RI-MUHC), McGill University, Montréal, QC, Canada.
  • Beautrait A; Department of Medicine, Research Institute of the McGill University Health Center (RI-MUHC), McGill University, Montréal, QC, Canada.
  • Armando S; Research Institute of the McGill University Health Center (RI-MUHC), Montreal, QC, Canada.
  • Radresa O; Department of Anatomy and Cell Biology, McGill University, Montréal, QC, Canada.
  • Duchaine J; Department of Pharmacology and Physiology, Université de Montréal, Montréal, QC, Canada.
  • Lamarche-Vane N; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, QC, Canada.
  • Claing A; Schrödinger, Inc., New York, NY, United States.
  • Selent J; Department of Medicine, Research Institute of the McGill University Health Center (RI-MUHC), McGill University, Montréal, QC, Canada.
  • Bouvier M; Department of Medicine, Research Institute of the McGill University Health Center (RI-MUHC), McGill University, Montréal, QC, Canada.
  • Marinier A; Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, QC, Canada.
  • Laporte SA; Research Institute of the McGill University Health Center (RI-MUHC), Montreal, QC, Canada.
Nat Commun ; 12(1): 4688, 2021 08 03.
Article en En | MEDLINE | ID: mdl-34344896
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas ras / Factores de Ribosilacion-ADP / Receptores Acoplados a Proteínas G / Endocitosis / Inhibidores Enzimáticos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas ras / Factores de Ribosilacion-ADP / Receptores Acoplados a Proteínas G / Endocitosis / Inhibidores Enzimáticos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Canadá