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An experimental approach probing the conformational transitions and energy landscape of antibodies: a glimmer of hope for reviving lost therapeutic candidates using ionic liquid.
Shmool, Talia A; Martin, Laura K; Bui-Le, Liem; Moya-Ramirez, Ignacio; Kotidis, Pavlos; Matthews, Richard P; Venter, Gerhard A; Kontoravdi, Cleo; Polizzi, Karen M; Hallett, Jason P.
Afiliación
  • Shmool TA; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
  • Martin LK; Department of Engineering Science, University of Oxford Parks Road Oxford OX1 3PJ UK.
  • Bui-Le L; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
  • Moya-Ramirez I; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
  • Kotidis P; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
  • Matthews RP; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
  • Venter GA; Scientific Computing Research Unit, Department of Chemistry, University of Cape Town Rondebosch Cape Town 7701 South Africa.
  • Kontoravdi C; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
  • Polizzi KM; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
  • Hallett JP; Department of Chemical Engineering, Imperial College London South Kensington Campus London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
Chem Sci ; 12(27): 9528-9545, 2021 Jul 14.
Article en En | MEDLINE | ID: mdl-34349928
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Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Sci Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Chem Sci Año: 2021 Tipo del documento: Article