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Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy.
Siolas, Despina; Vucic, Emily; Kurz, Emma; Hajdu, Cristina; Bar-Sagi, Dafna.
Afiliación
  • Siolas D; Department of Medicine, New York University Grossman School of Medicine, New York, NY, USA; Laura and Isaac Perlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY, USA. Electronic address: despina.siolas@nyulangone.org.
  • Vucic E; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA.
  • Kurz E; Molecular Oncology and Tumor Immunology Training Program, NYU Grossman School of Medicine, New York, NY, USA.
  • Hajdu C; Department of Pathology, NYU Langone Health, New York, NY, USA.
  • Bar-Sagi D; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA. Electronic address: dafna.bar-sagi@nyulangone.org.
Cell Rep ; 36(8): 109578, 2021 08 24.
Article en En | MEDLINE | ID: mdl-34433022
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteína p53 Supresora de Tumor / Infiltración Neutrófila / Carcinoma Ductal Pancreático / Mutación con Ganancia de Función / Inmunoterapia / Neutrófilos Límite: Animals Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteína p53 Supresora de Tumor / Infiltración Neutrófila / Carcinoma Ductal Pancreático / Mutación con Ganancia de Función / Inmunoterapia / Neutrófilos Límite: Animals Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article