Towards an advanced testing strategy for genotoxicity using image-based 2D and 3D HepG2 DNA damage response fluorescent protein reporters.

Ter Braak, Bas; Niemeijer, Marije; Wolters, Liesanne; Le Dévédec, Sylvia; Bouwman, Peter; van de Water, Bob

Ter Braak, Bas; Niemeijer, Marije; Wolters, Liesanne; Le Dévédec, Sylvia; Bouwman, Peter; van de Water, Bob.

Afiliación

Ter Braak B; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Niemeijer M; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Wolters L; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Le Dévédec S; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
Bouwman P; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.
van de Water B; Division of Drug Discovery and Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.

Mutagenesis ; 37(2): 130-142, 2022 05 04.

Article en En | MEDLINE | ID: mdl-34448005

Asunto(s)

Daño del ADN; Proteína p53 Supresora de Tumor; Células Hep G2; Humanos; Pruebas de Mutagenicidad/métodos; Mutágenos/toxicidad; Proteína p53 Supresora de Tumor/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Daño del ADN / Proteína p53 Supresora de Tumor Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Mutagenesis Asunto de la revista: GENETICA MEDICA / SAUDE AMBIENTAL Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos

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