Quantitative Structure-Activity Relationships of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents.

Wunsch, Friederike M; Wünsch, Bernhard; Bernal, Freddy A; Schmidt, Thomas J

Wunsch, Friederike M; Wünsch, Bernhard; Bernal, Freddy A; Schmidt, Thomas J.

Afiliación

Wunsch FM; Institute of Pharmaceutical Biology and Phytochemistry (IPBP), University of Münster, PharmaCampus, Corrensstrasse 48, 48149 Münster, Germany.
Wünsch B; Institute of Pharmaceutical and Medicinal Chemistry (IPMC), University of Münster, PharmaCampus, Corrensstrasse 48, 48149 Münster, Germany.
Bernal FA; Institute of Pharmaceutical Biology and Phytochemistry (IPBP), University of Münster, PharmaCampus, Corrensstrasse 48, 48149 Münster, Germany.
Schmidt TJ; Transfer Group Anti-Infectives, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute (HKI), Beutenbergstraße 11a, 07745 Jena, Germany.

Molecules ; 26(17)2021 Aug 30.

Article en En | MEDLINE | ID: mdl-34500683

Asunto(s)

Antimaláricos/química; Benzopiranos/química; Productos Biológicos/química; Plasmodium falciparum/efectos de los fármacos; Relación Estructura-Actividad Cuantitativa

Palabras clave

3D-QSAR; Plasmodium falciparum; aminoalkyl benzopyran; aminoalkyl chromane; aminoalkyl chromene; malaria; structureactivity relationship

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Benzopiranos / Antimaláricos Tipo de estudio: Prognostic_studies Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania

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