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Increased somatic mutation burdens in normal human cells due to defective DNA polymerases.
Robinson, Philip S; Coorens, Tim H H; Palles, Claire; Mitchell, Emily; Abascal, Federico; Olafsson, Sigurgeir; Lee, Bernard C H; Lawson, Andrew R J; Lee-Six, Henry; Moore, Luiza; Sanders, Mathijs A; Hewinson, James; Martin, Lynn; Pinna, Claudia M A; Galavotti, Sara; Rahbari, Raheleh; Campbell, Peter J; Martincorena, Iñigo; Tomlinson, Ian; Stratton, Michael R.
Afiliación
  • Robinson PS; Wellcome Sanger Institute, Hinxton, UK.
  • Coorens THH; Department of Paediatrics, University of Cambridge, Cambridge, UK.
  • Palles C; Wellcome Sanger Institute, Hinxton, UK.
  • Mitchell E; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
  • Abascal F; Wellcome Sanger Institute, Hinxton, UK.
  • Olafsson S; Wellcome Sanger Institute, Hinxton, UK.
  • Lee BCH; Wellcome Sanger Institute, Hinxton, UK.
  • Lawson ARJ; Wellcome Sanger Institute, Hinxton, UK.
  • Lee-Six H; Hereditary Gastrointestinal Cancer Genetic Diagnosis Laboratory, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.
  • Moore L; Wellcome Sanger Institute, Hinxton, UK.
  • Sanders MA; Wellcome Sanger Institute, Hinxton, UK.
  • Hewinson J; Wellcome Sanger Institute, Hinxton, UK.
  • Martin L; Wellcome Sanger Institute, Hinxton, UK.
  • Pinna CMA; Department of Haematology, Erasmus University Medical Centre, Rotterdam, the Netherlands.
  • Galavotti S; Wellcome Sanger Institute, Hinxton, UK.
  • Rahbari R; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
  • Campbell PJ; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
  • Martincorena I; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.
  • Tomlinson I; Wellcome Sanger Institute, Hinxton, UK.
  • Stratton MR; Wellcome Sanger Institute, Hinxton, UK.
Nat Genet ; 53(10): 1434-1442, 2021 10.
Article en En | MEDLINE | ID: mdl-34594041
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Mutación de Línea Germinal / ADN Polimerasa II / ADN Polimerasa III Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Mutación de Línea Germinal / ADN Polimerasa II / ADN Polimerasa III Tipo de estudio: Prognostic_studies Límite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Revista: Nat Genet Asunto de la revista: GENETICA MEDICA Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido