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Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection.
Smith-Peter, Erich; Séguin, David Lalonde; St-Pierre, Émilie; Sekulovic, Ognjen; Jeanneau, Simon; Tremblay-Tétreault, Cédrick; Lamontagne, Anne-Marie; Jacques, Pierre-Étienne; Lafontaine, Daniel A; Fortier, Louis-Charles.
Afiliación
  • Smith-Peter E; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Séguin DL; Department of Biology, Faculty of Science, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • St-Pierre É; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Sekulovic O; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Jeanneau S; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Tremblay-Tétreault C; Department of Biology, Faculty of Science, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Lamontagne AM; Department of Biology, Faculty of Science, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Jacques PÉ; Department of Biology, Faculty of Science, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Lafontaine DA; Department of Biology, Faculty of Science, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
  • Fortier LC; Department of Biology, Faculty of Science, Université De Sherbrooke, Sherbrooke, Quebec, Canada.
RNA Biol ; 18(sup2): 699-710, 2021 11 12.
Article en En | MEDLINE | ID: mdl-34612173
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Regulación Bacteriana de la Expresión Génica / Clostridioides difficile / Infecciones por Clostridium / Ligasas de Carbono-Nitrógeno / Riboswitch Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: RNA Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Regulación Bacteriana de la Expresión Génica / Clostridioides difficile / Infecciones por Clostridium / Ligasas de Carbono-Nitrógeno / Riboswitch Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: RNA Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article País de afiliación: Canadá