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The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis.
Heida, Andries; Gruben, Nanda; Catrysse, Leen; Koehorst, Martijn; Koster, Mirjam; Kloosterhuis, Niels J; Gerding, Albert; Havinga, Rick; Bloks, Vincent W; Bongiovanni, Laura; Wolters, Justina C; van Dijk, Theo; van Loo, Geert; de Bruin, Alain; Kuipers, Folkert; Koonen, Debby P Y; van de Sluis, Bart.
Afiliación
  • Heida A; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Gruben N; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Catrysse L; VIB Inflammation Research Center, Ghent University, Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Koehorst M; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Koster M; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Kloosterhuis NJ; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Gerding A; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Havinga R; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Bloks VW; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Bongiovanni L; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, the Netherlands; Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
  • Wolters JC; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • van Dijk T; Departments of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • van Loo G; VIB Inflammation Research Center, Ghent University, Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • de Bruin A; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, the Netherlands.
  • Kuipers F; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Departments of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Koonen DPY; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address: D.P.Y.Koonen@umcg.nl.
  • van de Sluis B; Departments of Pediatrics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address: A.J.A.van.de.Sluis@umcg.nl.
Mol Metab ; 54: 101349, 2021 12.
Article en En | MEDLINE | ID: mdl-34626855
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Colesterol / FN-kappa B / Quinasa I-kappa B / Lipogénesis / Enfermedad del Hígado Graso no Alcohólico Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Metab Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Colesterol / FN-kappa B / Quinasa I-kappa B / Lipogénesis / Enfermedad del Hígado Graso no Alcohólico Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Metab Año: 2021 Tipo del documento: Article País de afiliación: Países Bajos