LDL receptor and pathogen processes: Functions beyond normal lipids.
J Clin Lipidol
; 15(6): 773-781, 2021.
Article
en En
| MEDLINE
| ID: mdl-34645587
ABSTRACT
Although the role of the LDL receptor concerning lipids is well known, its role in various viral and parasitic infections, and in regulating the inflammatory response is poorly understood. Several infectious agents use the LDL receptor as a port of entry, and others depend on it for their cycle of infection. In this review, we focus on the discovery, structure, and normal function of the LDL receptor, as well as its role in a selection of infections. The LDL receptor plays an important role in certain infections and is a potential target for treatment deserving further research.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Toxoplasma
/
Trypanosoma cruzi
/
Receptores de LDL
/
Virus de la Estomatitis Vesicular Indiana
/
Hepacivirus
/
Lipoproteínas LDL
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Clin Lipidol
Asunto de la revista:
BIOQUIMICA
/
METABOLISMO
Año:
2021
Tipo del documento:
Article