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Key Substitutions in the Spike Protein of SARS-CoV-2 Variants Can Predict Resistance to Monoclonal Antibodies, but Other Substitutions Can Modify the Effects.
Lusvarghi, Sabrina; Wang, Wei; Herrup, Rachel; Neerukonda, Sabari Nath; Vassell, Russell; Bentley, Lisa; Eakin, Ann E; Erlandson, Karl J; Weiss, Carol D.
Afiliación
  • Lusvarghi S; Division of Viral Product, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Wang W; Division of Viral Product, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Herrup R; Division of Viral Product, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Neerukonda SN; Division of Viral Product, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Vassell R; Division of Viral Product, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
  • Bentley L; Office of the Assistant Secretary for Preparedness and Response, U.S. Department of Human Health and Services, Washington, DC, USA.
  • Eakin AE; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA.
  • Erlandson KJ; Influenza and Emerging Infectious Diseases Division, Biomedical Advanced Research and Development Authority, U.S. Department of Health and Human Servicesgrid.428374.e, Washington, DC, United States of America.
  • Weiss CD; Division of Viral Product, Office of Vaccine Research and Review, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
J Virol ; 96(1): e0111021, 2022 01 12.
Article en En | MEDLINE | ID: mdl-34668774
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Glicoproteína de la Espiga del Coronavirus / SARS-CoV-2 / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Virol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Glicoproteína de la Espiga del Coronavirus / SARS-CoV-2 / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Virol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos