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Two new isoquinoline alkaloids from Cryptocarya wrayi and their biological activities.
Liu, Yun-Lai; Wang, Yong; He, Xiao-Ru; Gan, Li-She; Xu, Fan; Xu, Yun-Jing; Wang, Xiao-Ning; Shen, Tao; Zhou, Zhi-Wang.
Afiliación
  • Liu YL; School of Pharmacy, Nanchang University, Nanchang 330006, PR China.
  • Wang Y; School of Pharmacy, Nanchang University, Nanchang 330006, PR China.
  • He XR; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, PR China.
  • Gan LS; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, PR China; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, PR China. Electronic address: ganlishe@163.com.
  • Xu F; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, PR China.
  • Xu YJ; School of Pharmacy, Nanchang University, Nanchang 330006, PR China.
  • Wang XN; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan 250012, PR China.
  • Shen T; Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan 250012, PR China.
  • Zhou ZW; School of Pharmacy, Nanchang University, Nanchang 330006, PR China; Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of TCM, Nanchang 330004, PR China. Electronic address: zhouzw@ncu.edu.cn.
Fitoterapia ; 156: 105086, 2022 Jan.
Article en En | MEDLINE | ID: mdl-34798164
ABSTRACT
Two new isoquinoline alkaloids, cryptowrayines A (1) and B (2), along with one known pavine alkaloid (-)-12-hydroxyeschscholtzidine (3), were isolated from the twigs of Cryptocarya wrayi. The structures of new compounds were elucidated by extensive spectroscopic data analysis and electronic circular dichroism (ECD) calculations. Both compounds 1 and 2 exhibited moderate quinone reductase inducing activity in Hepa 1c1c7 cells.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cryptocarya / Alcaloides / Isoquinolinas Idioma: En Revista: Fitoterapia Año: 2022 Tipo del documento: Article
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cryptocarya / Alcaloides / Isoquinolinas Idioma: En Revista: Fitoterapia Año: 2022 Tipo del documento: Article