Vitamin D and COVID-19 Infection.
Med J Malaysia
; 76(6): 881-883, 2021 11.
Article
en En
| MEDLINE
| ID: mdl-34806677
ABSTRACT
INTRODUCTION:
The COVID-19 pandemic has prompted the medical world to look at factors that may influence outcomes. There have been connections made between vitamin D and COVID-19, as vitamin D has previously been shown to play a role in the maintenance of immune homeostasis. MATERIALS ANDMETHODS:
We performed a prospective cohort study on 103 patients at Wigan Wrightington and Leigh NHS Foundation Trust looking at serum vitamin D levels of patients with positive COVID-19 swabs. Results were collated and correlations were made to compare vitamin D levels with age; severity of illness; hospital outcomes; and frailty. Comparisons were also made between frailty and outcome.RESULTS:
The results showed that there was a significant statistical difference between vitamin D levels and severity of infection those who were treated in the intensive care units (ICU) (severe symptoms) had lower vitamin D levels than those treated on the ward (p=0.0446). There was also a correlation between vitamin D levels and frailty those who were more frail had higher vitamin D levels than fitter patients (P=0.005). Vitamin D and frailty had no effect on hospital outcomes of COVID-19 infection.CONCLUSION:
Ultimately, we concluded that low vitamin D can increase susceptibility of contracting COVID-19, increase severity of infection but does not affect mortality.
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Base de datos:
MEDLINE
Asunto principal:
Deficiencia de Vitamina D
/
COVID-19
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Med J Malaysia
Año:
2021
Tipo del documento:
Article
País de afiliación:
Reino Unido