Alterations in T-Cell Transcription Factors and Cytokine Gene Expression in Late-Onset Alzheimer's Disease.

Neshan, Masoud; Malakouti, Seyed Kazem; Kamalzadeh, Leila; Makvand, Mina; Campbell, Arezoo; Ahangari, Ghasem

Neshan, Masoud; Malakouti, Seyed Kazem; Kamalzadeh, Leila; Makvand, Mina; Campbell, Arezoo; Ahangari, Ghasem.

Afiliación

Neshan M; Department of Medical Genetics, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Malakouti SK; Mental Health Research Center, Tehran Institute of Psychiatry - School of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran.
Kamalzadeh L; Mental Health Research Center, Tehran Institute of Psychiatry - School of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran.
Makvand M; Department of Medical Genetics, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Campbell A; Department of Pharmaceutical Sciences, Western University of Health Sciences, Pomona, CA, USA.
Ahangari G; Department of Medical Genetics, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.

J Alzheimers Dis ; 85(2): 645-665, 2022.

Article en En | MEDLINE | ID: mdl-34864659

Asunto(s)

Enfermedad de Alzheimer/genética; Leucocitos Mononucleares/metabolismo; Células Th17/metabolismo; Edad de Inicio; Anciano; Anciano de 80 o más Años; Enfermedad de Alzheimer/inmunología; Enfermedad de Alzheimer/patología; Estudios de Casos y Controles; Femenino; Factor de Transcripción GATA3/genética; Factor de Transcripción GATA3/metabolismo; Regulación de la Expresión Génica; Humanos; Interferón gamma/genética; Interferón gamma/metabolismo; Masculino; ARN Mensajero/genética; ARN Mensajero/metabolismo; Proteínas de Dominio T Box/genética; Proteínas de Dominio T Box/metabolismo; Células Th17/patología; Factor de Necrosis Tumoral alfa/genética; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Alzheimer's disease; LOAD; T helper cell; Th17 cell; cytokine; gene expression; mitogen-activated protein kinase; protein-protein interaction; transcription factor

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Leucocitos Mononucleares / Células Th17 / Enfermedad de Alzheimer Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: J Alzheimers Dis Asunto de la revista: GERIATRIA / NEUROLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Irán

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