Gene therapy with SOCS1 induces potent preclinical antitumor activities in oral squamous cell carcinoma.

Nakatani, Kie; Serada, Satoshi; Fujimoto, Minoru; Obata, Kengo; Ohkawara, Tomoharu; Sasabe, Eri; Yamamoto, Tetsuya; Naka, Tetsuji

Nakatani, Kie; Serada, Satoshi; Fujimoto, Minoru; Obata, Kengo; Ohkawara, Tomoharu; Sasabe, Eri; Yamamoto, Tetsuya; Naka, Tetsuji.

Afiliación

Nakatani K; Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University, Nankoku, Japan.
Serada S; Department of Clinical Immunology, Kochi Medical School, Kochi University, Nankoku, Japan.
Fujimoto M; Institute for Biomedical Sciences Molecular Pathophysiology, Iwate Medical University, Yahaba, Japan.
Obata K; Department of Clinical Immunology, Kochi Medical School, Kochi University, Nankoku, Japan.
Ohkawara T; Division of Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Yahaba, Japan.
Sasabe E; Division of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Reconstructive Surgery, School of Dentistry, Iwate Medical University, Morioka, Japan.
Yamamoto T; Division of Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Yahaba, Japan.
Naka T; Department of Oral and Maxillofacial Surgery, Kochi Medical School, Kochi University, Nankoku, Japan.

J Oral Pathol Med ; 51(2): 126-133, 2022 Feb.

Article en En | MEDLINE | ID: mdl-34878693

Asunto(s)

Neoplasias de Cabeza y Cuello; Neoplasias de la Boca; Carcinoma de Células Escamosas de Cabeza y Cuello; Animales; Apoptosis/genética; Línea Celular Tumoral; Proliferación Celular/genética; Terapia Genética; Humanos; Ratones; Neoplasias de la Boca/genética; Neoplasias de la Boca/terapia; Factor de Transcripción STAT3/genética; Transducción de Señal; Carcinoma de Células Escamosas de Cabeza y Cuello/genética; Carcinoma de Células Escamosas de Cabeza y Cuello/terapia; Proteína 1 Supresora de la Señalización de Citocinas/genética

Palabras clave

apoptosis; cell cycle; oral squamous cell carcinoma; signal transducer and activator of transcription-3; suppressor of cytokine signaling-1

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas de Cabeza y Cuello / Neoplasias de Cabeza y Cuello Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Oral Pathol Med Asunto de la revista: ODONTOLOGIA / PATOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Japón

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