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Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.
Li, Qiang; Feng, Hui; Wang, Hongbo; Wang, Yinghao; Mou, Wenqing; Xu, Guang; Zhang, Ping; Li, Ruisheng; Shi, Wei; Wang, Zhilei; Fang, Zhie; Ren, Lutong; Wang, Yan; Lin, Li; Hou, Xiaorong; Dai, Wenzhang; Li, Zhiyong; Wei, Ziying; Liu, Tingting; Wang, Jiabo; Guo, Yuming; Li, Pengyan; Zhao, Xu; Zhan, Xiaoyan; Xiao, Xiaohe; Bai, Zhaofang.
Afiliación
  • Li Q; School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
  • Feng H; Department of Hepatology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Wang H; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Wang Y; Department of Ultrasound, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Mou W; Department of Hepatology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Xu G; School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
  • Zhang P; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Li R; Department of Hepatology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Shi W; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Wang Z; Department of Hepatology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Fang Z; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Ren L; Research Center for Clinical and Translational Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Wang Y; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Lin L; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Hou X; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Dai W; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Li Z; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Wei Z; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Liu T; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Wang J; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Guo Y; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Li P; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Zhao X; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Zhan X; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Xiao X; Department of Hepatology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Bai Z; China Military Institute of Chinese Materia, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
EMBO Rep ; 23(2): e53499, 2022 02 03.
Article en En | MEDLINE | ID: mdl-34882936
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Chalconas / Inflamasomas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EMBO Rep Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Chalconas / Inflamasomas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EMBO Rep Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: China