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RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors.
Roulston, Anne; Zimmermann, Michal; Papp, Robert; Skeldon, Alexander; Pellerin, Charles; Dumas-Bérube, Émilie; Dumais, Valerie; Dorich, Stéphane; Fader, Lee D; Fournier, Sara; Li, Li; Leclaire, Marie-Eve; Yin, Shou Yun; Chefson, Amandine; Alam, Hunain; Yang, William; Fugère-Desjardins, Chloe; Vignini-Hammond, Sabrina; Skorey, Kathryn; Mulani, Amina; Rimkunas, Victoria; Veloso, Artur; Hamel, Martine; Stocco, Rino; Mamane, Yael; Li, Zuomei; Young, Jordan T F; Zinda, Michael; Black, W Cameron.
Afiliación
  • Roulston A; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada. aroulston@reparerx.com.
  • Zimmermann M; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Papp R; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Skeldon A; Ventus Therapeutics Inc. Saint-Laurent, Quebec, Canada.
  • Pellerin C; Ventus Therapeutics Inc. Saint-Laurent, Quebec, Canada.
  • Dumas-Bérube É; Ventus Therapeutics Inc. Saint-Laurent, Quebec, Canada.
  • Dumais V; Ventus Therapeutics Inc. Saint-Laurent, Quebec, Canada.
  • Dorich S; Ventus Therapeutics Inc. Saint-Laurent, Quebec, Canada.
  • Fader LD; Ventus Therapeutics Inc. Saint-Laurent, Quebec, Canada.
  • Fournier S; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Li L; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Leclaire ME; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Yin SY; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Chefson A; Ventus Therapeutics Inc. Saint-Laurent, Quebec, Canada.
  • Alam H; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Yang W; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Fugère-Desjardins C; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Vignini-Hammond S; NuChem Sciences Inc. Saint-Laurent, Quebec, Canada.
  • Skorey K; NuChem Sciences Inc. Saint-Laurent, Quebec, Canada.
  • Mulani A; NuChem Sciences Inc. Saint-Laurent, Quebec, Canada.
  • Rimkunas V; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Veloso A; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Hamel M; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Stocco R; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Mamane Y; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Li Z; NuChem Sciences Inc. Saint-Laurent, Quebec, Canada.
  • Young JTF; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Zinda M; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
  • Black WC; Repare Therapeutics Inc., Saint-Laurent, Quebec, Canada.
Mol Cancer Ther ; 21(2): 245-256, 2022 02.
Article en En | MEDLINE | ID: mdl-34911817
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ataxia Telangiectasia / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2022 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ataxia Telangiectasia / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2022 Tipo del documento: Article País de afiliación: Canadá