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Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
Ambike, Shubhankar; Cheng, Cho-Chin; Feuerherd, Martin; Velkov, Stoyan; Baldassi, Domizia; Afridi, Suliman Qadir; Porras-Gonzalez, Diana; Wei, Xin; Hagen, Philipp; Kneidinger, Nikolaus; Stoleriu, Mircea Gabriel; Grass, Vincent; Burgstaller, Gerald; Pichlmair, Andreas; Merkel, Olivia M; Ko, Chunkyu; Michler, Thomas.
Afiliación
  • Ambike S; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Cheng CC; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Feuerherd M; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Velkov S; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Baldassi D; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstraße 5, 81377 Munich, Germany.
  • Afridi SQ; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Porras-Gonzalez D; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Wei X; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Hagen P; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Kneidinger N; Department of Medicine V, University Hospital, LMU Munich, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Stoleriu MG; Center for Thoracic Surgery Munich, Ludwig-Maximilians-University of Munich (LMU) and Asklepios Pulmonary Hospital; Marchioninistraße 15, 81377 Munich and Robert-Koch-Allee 2, 82131 Gauting, Germany.
  • Grass V; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Burgstaller G; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.
  • Pichlmair A; Institute of Virology, School of Medicine, Technische Universität München / Helmholtz Zentrum München, Trogerstr. 30, 81675 Munich, Germany.
  • Merkel OM; German Center for Infection Research (DZIF), Munich partner site, Germany.
  • Ko C; Department of Pharmacy, Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-Universität München, Butenandtstraße 5, 81377 Munich, Germany.
  • Michler T; Institute of Lung Biology and Disease (ILBD) and Comprehensive Pneumology Center (CPC) with the CPC-M bioArchive, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany.
Nucleic Acids Res ; 50(1): 333-349, 2022 01 11.
Article en En | MEDLINE | ID: mdl-34928377
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Replicación Viral / ARN Viral / ARN Interferente Pequeño / SARS-CoV-2 / COVID-19 / Pulmón Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2022 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Replicación Viral / ARN Viral / ARN Interferente Pequeño / SARS-CoV-2 / COVID-19 / Pulmón Límite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Año: 2022 Tipo del documento: Article País de afiliación: Alemania