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Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells.
Costanzo, Federico; Martínez Diez, Marta; Santamaría Nuñez, Gema; Díaz-Hernandéz, Juan Ignacio; Genes Robles, Carlos Mario; Díez Pérez, Javier; Compe, Emmanuel; Ricci, Romeo; Li, Tsai-Kun; Coin, Frédéric; Martínez Leal, Juan Fernando; Garrido-Martin, Eva Maria; Egly, Jean Marc.
Afiliación
  • Costanzo F; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, Equipe labellisée Ligue contre le Cancer, Strasbourg, France.
  • Martínez Diez M; Cell Biology Department, Research and Development, Pharmamar SA, Colmenar Viejo, Spain.
  • Santamaría Nuñez G; Cell Biology Department, Research and Development, Pharmamar SA, Colmenar Viejo, Spain.
  • Díaz-Hernandéz JI; Cell Biology Department, Research and Development, Pharmamar SA, Colmenar Viejo, Spain.
  • Genes Robles CM; Cell Biology Department, Research and Development, Pharmamar SA, Colmenar Viejo, Spain.
  • Díez Pérez J; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, Equipe labellisée Ligue contre le Cancer, Strasbourg, France.
  • Compe E; Cell Biology Department, Research and Development, Pharmamar SA, Colmenar Viejo, Spain.
  • Ricci R; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, Equipe labellisée Ligue contre le Cancer, Strasbourg, France.
  • Li TK; Laboratoire de Biochimie et de Biologie Moléculaire, Nouvel Hôpital Civil, Strasbourg, France.
  • Coin F; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, Equipe labellisée Ligue contre le Cancer, Strasbourg, France.
  • Martínez Leal JF; Laboratoire de Biochimie et de Biologie Moléculaire, Nouvel Hôpital Civil, Strasbourg, France.
  • Garrido-Martin EM; College of Medicine, Center for Genomics and Precision Medicine, National Taiwan University, Taipei city, Taiwan.
  • Egly JM; Department of Functional Genomics and Cancer, IGBMC, CNRS/INSERM/University of Strasbourg, Equipe labellisée Ligue contre le Cancer, Strasbourg, France.
EMBO Mol Med ; 14(4): e14841, 2022 04 07.
Article en En | MEDLINE | ID: mdl-35263037

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Represoras / Carbolinas / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Carcinoma Pulmonar de Células Pequeñas / Compuestos Heterocíclicos de 4 o más Anillos / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Francia

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Represoras / Carbolinas / Factores de Transcripción con Motivo Hélice-Asa-Hélice Básico / Carcinoma Pulmonar de Células Pequeñas / Compuestos Heterocíclicos de 4 o más Anillos / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2022 Tipo del documento: Article País de afiliación: Francia