[The effectiveness of transtympanic use of dexamethasone 4 mg in Meniere's disease, severe and moderate course of the disease]. / Effektivnost' transtimpanal'nogo primeneniya deksametazona 4 mg pri bolezni Men'era, tyazhelom i srednetyazhelom techenii zabolevaniya.
Vestn Otorinolaringol
; 87(1): 21-26, 2022.
Article
en Ru
| MEDLINE
| ID: mdl-35274888
ABSTRACT
The results of transtympanic administration of 4 mg dexamethasone in 37 patients with moderate and severe Meniere's disease are presented. The endolymphatic hydrops was detected in all inner ear structures with predominant accumulation in vestibule and semicircular canals by MRI-visualization before therapy. After 1 month of 4 mg dexamethasone transtympanic therapy the hydrops degree decreased. Daily transtympanic administration of 4 mg dexamethasone for a month leads to reduction of vertigo attacks duration and expression in 92% of cases (follow-up period 24 months) and can be considered when conservative therapy is ineffective before destructive surgical interventions.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Vestíbulo del Laberinto
/
Hidropesía Endolinfática
/
Enfermedad de Meniere
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
Ru
Revista:
Vestn Otorinolaringol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Rusia