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Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms.
Ma, Zhixiong; Eaton, Muriel; Liu, Yushuang; Zhang, Jingliang; Chen, Xiaoling; Tu, Xinyu; Shi, Yiqiang; Que, Zhefu; Wettschurack, Kyle; Zhang, Zaiyang; Shi, Riyi; Chen, Yueyi; Kimbrough, Adam; Lanman, Nadia A; Schust, Leah; Huang, Zhuo; Yang, Yang.
Afiliación
  • Ma Z; State Key Laboratory of Natural and Biomimetic Drugs, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue I
  • Eaton M; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN 47906, USA.
  • Liu Y; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN 47906, USA.
  • Zhang J; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN 47906, USA.
  • Chen X; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN 47906, USA.
  • Tu X; State Key Laboratory of Natural and Biomimetic Drugs, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
  • Shi Y; State Key Laboratory of Natural and Biomimetic Drugs, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
  • Que Z; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN 47906, USA.
  • Wettschurack K; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN 47906, USA.
  • Zhang Z; Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA.
  • Shi R; Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA.
  • Chen Y; Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA.
  • Kimbrough A; Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA.
  • Lanman NA; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47906, USA.
  • Schust L; FamilieSCN2A Foundation, P.O. Box 82, East Longmeadow, MA 01028, USA.
  • Huang Z; State Key Laboratory of Natural and Biomimetic Drugs, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China. Electronic address: huangz@hsc.pku.edu.cn.
  • Yang Y; Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy & Purdue Institute for Integrative Neuroscience, Purdue University, West Lafayette, IN 47906, USA. Electronic address: yangyang@purdue.edu.
Neurobiol Dis ; 168: 105690, 2022 06 15.
Article en En | MEDLINE | ID: mdl-35301122
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Trastorno Autístico / Canal de Sodio Activado por Voltaje NAV1.2 / Trastorno del Espectro Autista Límite: Animals Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Trastorno Autístico / Canal de Sodio Activado por Voltaje NAV1.2 / Trastorno del Espectro Autista Límite: Animals Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2022 Tipo del documento: Article