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Effectiveness of the Ad26.COV2.S vaccine in health-care workers in South Africa (the Sisonke study): results from a single-arm, open-label, phase 3B, implementation study.
Bekker, Linda-Gail; Garrett, Nigel; Goga, Ameena; Fairall, Lara; Reddy, Tarylee; Yende-Zuma, Nonhlanhla; Kassanjee, Reshma; Collie, Shirley; Sanne, Ian; Boulle, Andrew; Seocharan, Ishen; Engelbrecht, Imke; Davies, Mary-Ann; Champion, Jared; Chen, Tommy; Bennett, Sarah; Mametja, Selaelo; Semenya, Mabatlo; Moultrie, Harry; de Oliveira, Tulio; Lessells, Richard John; Cohen, Cheryl; Jassat, Waasila; Groome, Michelle; Von Gottberg, Anne; Le Roux, Engelbert; Khuto, Kentse; Barouch, Dan; Mahomed, Hassan; Wolmarans, Milani; Rousseau, Petro; Bradshaw, Debbie; Mulder, Michelle; Opie, Jessica; Louw, Vernon; Jacobson, Barry; Rowji, Pradeep; Peter, Jonny G; Takalani, Azwi; Odhiambo, Jackline; Mayat, Fatima; Takuva, Simbarashe; Corey, Lawrence; Gray, Glenda E.
Afiliación
  • Bekker LG; The Desmond Tutu HIV Centre, Cape Town, South Africa; University of Cape Town, Cape Town, South Africa.
  • Garrett N; Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa.
  • Goga A; HIV Prevention Research Unit, Cape Town, South Africa; Department of Paediatrics and Child Health, University of Pretoria, Pretoria, South Africa.
  • Fairall L; The Desmond Tutu HIV Centre, Cape Town, South Africa; King's Global Health Institute, King's College London, London, UK.
  • Reddy T; Biostatistics Research Unit, South African Medical Research Council, Durban, South Africa.
  • Yende-Zuma N; Nelson R Mandela School of Medicine, Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban, South Africa.
  • Kassanjee R; Centre of Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Cape Town, South Africa.
  • Collie S; Discovery Health, Sandton, South Africa.
  • Sanne I; Clinical HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Witwatersrand, South Africa; Right to Care, Houghton South Africa.
  • Boulle A; Centre of Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Cape Town, South Africa; Western Cape Government Health, Cape Town, South Africa; Wellcome Centre for Infectious Diseases Research in Africa, Cape Town, South Africa.
  • Seocharan I; Biostatistics Research Unit, South African Medical Research Council, Durban, South Africa.
  • Engelbrecht I; Right to Care, Centurion, South Africa.
  • Davies MA; Centre of Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Cape Town, South Africa; Western Cape Government: Health Centre for Infectious Disease Epidemiology and Research, Cape Town, South Africa.
  • Champion J; Discovery Health, Sandton, South Africa.
  • Chen T; Discovery Health, Sandton, South Africa.
  • Bennett S; Medscheme, Cape Town, South Africa.
  • Mametja S; Government Employees Medical Scheme, Pretoria, South Africa.
  • Semenya M; Government Employees Medical Scheme, Pretoria, South Africa.
  • Moultrie H; Centre for Tuberculosis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • de Oliveira T; KwaZulu-Natal Research Innovation, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
  • Lessells RJ; KwaZulu-Natal Research Innovation, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
  • Cohen C; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Witwatersrand, South Africa; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa.
  • Jassat W; National Institute for Communicable Diseases, Sandringham, South Africa.
  • Groome M; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Witwatersrand, South Africa; Division of Public Health Surveillance and Response, National Institute for Communicable Diseases, Johannesburg, South Africa.
  • Von Gottberg A; Department of Pathology, Cape Town, South Africa; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Witwatersrand, South Africa; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Joh
  • Le Roux E; Hutchinson Center Research Institute of South Africa (HCRISA), Chris Hani Baragwanath Academic Hospital, Soweto, South Africa.
  • Khuto K; Hutchinson Center Research Institute of South Africa (HCRISA), Chris Hani Baragwanath Academic Hospital, Soweto, South Africa.
  • Barouch D; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
  • Mahomed H; Metro Health Services, Western Cape Government Health, Cape Town, South Africa; Division of Health Systems and Public Health, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
  • Wolmarans M; National Department of Health, Pretoria, South Africa.
  • Rousseau P; National Department of Health, Pretoria, South Africa.
  • Bradshaw D; South African Medical Research Council, Tygerberg, South Africa.
  • Mulder M; South Africa Medical Research Council, Cape Town, South Africa.
  • Opie J; University of Cape Town, Cape Town, South Africa; National Health Laboratory Service, Cape Town, South Africa.
  • Louw V; Division of Clinical Haematology, Department of Medicine, Cape Town, South Africa; Groote Schuur Hospital, Cape Town, South Africa.
  • Jacobson B; Faculty of Health Sciences, and Allergy and Immunology Unit, Cape Town, South Africa.
  • Rowji P; Neurology Association of South Africa, The Southern African Society of Thrombosis and Haemostasis, Johannesburg, South Africa.
  • Peter JG; Division of Allergy and Clinical Immunology, Cape Town, South Africa.
  • Takalani A; Hutchinson Center Research Institute of South Africa (HCRISA), Chris Hani Baragwanath Academic Hospital, Soweto, South Africa.
  • Odhiambo J; Hutchinson Center Research Institute of South Africa (HCRISA), Chris Hani Baragwanath Academic Hospital, Soweto, South Africa.
  • Mayat F; Perinatal HIV Research Unit (PHRU), Chris Hani Baragwanath Academic Hospital, University of the Witwatersrand, Witwatersrand, South Africa.
  • Takuva S; School of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Corey L; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Gray GE; South Africa Medical Research Council, Cape Town, South Africa. Electronic address: glenda.gray@mrc.ac.za.
Lancet ; 399(10330): 1141-1153, 2022 03 19.
Article en En | MEDLINE | ID: mdl-35305740

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vacunas / Infecciones por VIH / COVID-19 Tipo de estudio: Clinical_trials / Evaluation_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male País/Región como asunto: Africa Idioma: En Revista: Lancet Año: 2022 Tipo del documento: Article País de afiliación: Sudáfrica

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vacunas / Infecciones por VIH / COVID-19 Tipo de estudio: Clinical_trials / Evaluation_studies Límite: Adolescent / Adult / Aged / Female / Humans / Male País/Región como asunto: Africa Idioma: En Revista: Lancet Año: 2022 Tipo del documento: Article País de afiliación: Sudáfrica