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Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19.
Apostolidis, Sokratis A; Sarkar, Amrita; Giannini, Heather M; Goel, Rishi R; Mathew, Divij; Suzuki, Aae; Baxter, Amy E; Greenplate, Allison R; Alanio, Cécile; Abdel-Hakeem, Mohamed; Oldridge, Derek A; Giles, Josephine R; Wu, Jennifer E; Chen, Zeyu; Huang, Yinghui Jane; Belman, Jonathan; Pattekar, Ajinkya; Manne, Sasikanth; Kuthuru, Oliva; Dougherty, Jeanette; Weiderhold, Brittany; Weisman, Ariel R; Ittner, Caroline A G; Gouma, Sigrid; Dunbar, Debora; Frank, Ian; Huang, Alexander C; Vella, Laura A; Reilly, John P; Hensley, Scott E; Rauova, Lubica; Zhao, Liang; Meyer, Nuala J; Poncz, Mortimer; Abrams, Charles S; Wherry, E John.
Afiliación
  • Apostolidis SA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Sarkar A; Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Giannini HM; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Goel RR; Division of Pulmonary, Allergy and Critical Care Medicine, Center for Translational Lung Biology, Lung Biology Institute, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Mathew D; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Suzuki A; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Baxter AE; Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, United States.
  • Greenplate AR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Alanio C; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Abdel-Hakeem M; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Oldridge DA; Immune Health™, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Giles JR; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Wu JE; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Chen Z; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Huang YJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Belman J; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Pattekar A; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Manne S; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, United States.
  • Kuthuru O; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Dougherty J; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Weiderhold B; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Weisman AR; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Ittner CAG; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Gouma S; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Dunbar D; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Frank I; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Huang AC; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Vella LA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Reilly JP; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Hensley SE; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Rauova L; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Zhao L; Immune Health™, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Meyer NJ; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Poncz M; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Abrams CS; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
  • Wherry EJ; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.
Front Immunol ; 13: 834988, 2022.
Article en En | MEDLINE | ID: mdl-35309299
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tromboembolia / Plaquetas / Complemento C5a / Receptores de IgG / Receptor de Anafilatoxina C5a / SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tromboembolia / Plaquetas / Complemento C5a / Receptores de IgG / Receptor de Anafilatoxina C5a / SARS-CoV-2 / COVID-19 Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos