The relationship between atopy and allergic contact dermatitis in Israeli patients.
Postepy Dermatol Alergol
; 39(1): 159-163, 2022 Feb.
Article
en En
| MEDLINE
| ID: mdl-35369630
ABSTRACT
Introduction:
Whether individuals with atopic diseases have a different risk of contact allergy compared to those who are non-atopic is controversial and data are conflicting.Aim:
To explore the association between atopy and allergic contact dermatitis (ACD). Material andmethods:
This retrospective cross-sectional study included 301 patients referred to a tertiary clinic to evaluate ACD. Demographic details including personal and familial mucosal or cutaneous atopic status were recorded. Patch tests were tailored to their clinical presentations and relevant exposures.Results:
At least 1 positive patch test reaction was observed in 177 patients (59% of the study cohort), of which 52% had a history of atopic diseases, compared with 44% of patients with a negative patch test result (p = 0.2). Additionally, 147 patients had an atopic background, of which 92 (62%) had ≥ 1 positive patch test result, compared with 55% of non-atopic patients (p = 0.2). Nickel sulphate was the most common contact allergen (13.4% of the patch test reactions).Conclusions:
We identified a positive tendency for atopic diseases among individuals with ACD and vice versa. Our study supports the aggregate data from previous studies despite the non-significant differences between the study and control groups. However, further research performed in larger populations of patients is necessary to evaluate the real association between atopy and ACD on a solid basis. Our results indicate the necessity of systematic patch testing in patient setups with atopic background and chronic dermatitis.
Texto completo:
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Base de datos:
MEDLINE
Tipo de estudio:
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Postepy Dermatol Alergol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Israel