Docosahexaenoic acid is potent against the growth of mature stages of Plasmodium falciparum; inhibition of hematin polymerization a possible target.

Ommi, Naidu Babu; Abdullah, Maaged; Guruprasad, Lalitha; Babu, Phanithi Prakash

Ommi, Naidu Babu; Abdullah, Maaged; Guruprasad, Lalitha; Babu, Phanithi Prakash.

Afiliación

Ommi NB; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad 500 046, Telangana, India.
Abdullah M; School of Chemistry, University of Hyderabad, Gachibowli, Hyderabad 500 046, Telangana, India.
Guruprasad L; School of Chemistry, University of Hyderabad, Gachibowli, Hyderabad 500 046, Telangana, India.
Babu PP; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad 500 046, Telangana, India. Electronic address: prakash@uohyd.ac.in.

Parasitol Int ; 89: 102581, 2022 Aug.

Article en En | MEDLINE | ID: mdl-35395394

Asunto(s)

Malaria Falciparum; Plasmodium; Animales; Ácidos Docosahexaenoicos/metabolismo; Ácidos Docosahexaenoicos/farmacología; Eritrocitos; Hemo/metabolismo; Hemo/farmacología; Hemina; Malaria Falciparum/metabolismo; Parasitemia; Plasmodium falciparum; Polimerizacion; Esquizontes/metabolismo; Trofozoítos/metabolismo

Palabras clave

Docosahexaenoic acid; Neutral lipid bodies; Plasmodium falciparum; Polyunsaturated fatty acids; ß-Hematin

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Plasmodium / Malaria Falciparum Límite: Animals Idioma: En Revista: Parasitol Int Asunto de la revista: PARASITOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: India

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