Validation of the Italian version of the pediatric CMT quality of life outcome measure.
J Peripher Nerv Syst
; 27(2): 127-130, 2022 06.
Article
en En
| MEDLINE
| ID: mdl-35416371
ABSTRACT
The pediatric Charcot-Marie-Tooth (CMT) specific quality of life (QOL) outcome measure (pCMT-QOL) is a recently developed and validated patient-reported measure of health QOL for children with CMT. The aim of this study was to provide and validate an Italian version of the pCMT-QOL. The original English version was translated and adapted into Italian using standard procedures. pCMT-QOL was administered to patients genetically diagnosed with CMT, aged 8 to 18 years. A retest was given 2 weeks later to assess reliability in all patients. A total of 22 patients (median age 14 years, DS 2.5; MF 11) affected with CMT (19 CMT1A, 2 CMT2A, 1 CMT2K) were assessed as part of their clinical visit. The Italian-pCMT-QOL demonstrate a high test-retest reliability. None of the patients experienced difficulty in completing the questionnaire, no further corrections were needed after administration in patients. The Italian-pCMT-QOL is a reliable, culturally adapted and comparable version of the original English pCMT-QOL. This questionnaire is expected to be valuable in monitoring disease progression and useful for future clinical trials in Italian-speaking children with CMT.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Calidad de Vida
/
Enfermedad de Charcot-Marie-Tooth
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Child
/
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
J Peripher Nerv Syst
Asunto de la revista:
NEUROLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Italia