Resistosomes at the interface of pathogens and plants.
Curr Opin Plant Biol
; 67: 102212, 2022 06.
Article
en En
| MEDLINE
| ID: mdl-35462196
ABSTRACT
Nucleotide-binding and leucine-rich repeat (NLR) proteins are a large family of intracellular immune receptors that detect specific pathogen effector proteins secreted into plant cells. Upon direct or indirect recognition of effector proteins, NLRs form higher-order oligomeric complexes termed resistosomes that trigger defence responses typically associated with a regulated cell death. Here, we review recent advances in our understanding of signalling mediated by plant NLR resistosomes. Emphasis is placed on discussing the activation mechanisms and biochemical functions of resistosomes. We also summarize the most recent research in structure-based rational engineering of NLRs. At the end, we outline challenging questions concerning the elucidation of resistosome signalling.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Inmunidad de la Planta
/
Proteínas NLR
Idioma:
En
Revista:
Curr Opin Plant Biol
Asunto de la revista:
BOTANICA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Alemania