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AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells.
Li, Huiyu; Liu, Zhida; Liu, Longchao; Zhang, Hongyi; Han, Chuanhui; Girard, Luc; Park, Hyunsil; Zhang, Anli; Dong, Chunbo; Ye, Jianfeng; Rayford, Austin; Peyton, Michael; Li, Xiaoguang; Avila, Kimberley; Cao, Xuezhi; Hu, Shuiqing; Alam, Md Maksudul; Akbay, Esra A; Solis, Luisa M; Behrens, Carmen; Hernandez-Ruiz, Sharia; Lu, Wei; Wistuba, Ignacio; Heymach, John V; Chisamore, Michael; Micklem, David; Gabra, Hani; Gausdal, Gro; Lorens, James B; Li, Bo; Fu, Yang-Xin; Minna, John D; Brekken, Rolf A.
Afiliación
  • Li H; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-8593, USA.
  • Liu Z; Cancer Biology Graduate Program, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Liu L; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Zhang H; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Han C; Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Girard L; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Park H; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-8593, USA.
  • Zhang A; Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Dong C; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-8593, USA.
  • Ye J; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Rayford A; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Peyton M; Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Li X; BerGenBio ASA, Bergen, Norway.
  • Avila K; Department of Biomedicine, Centre for Cancer Biomarkers, Norwegian Centre of Excellence, University of Bergen, Bergen, Norway.
  • Cao X; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-8593, USA.
  • Hu S; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Alam MM; Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-8593, USA.
  • Akbay EA; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Solis LM; Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA.
  • Behrens C; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Hernandez-Ruiz S; Department of Pathology, UT Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9072, USA.
  • Lu W; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wistuba I; Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Heymach JV; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Chisamore M; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Micklem D; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Gabra H; Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Gausdal G; Merck & Co., Inc., Kenilworth, NJ 07033, USA.
  • Lorens JB; BerGenBio ASA, Bergen, Norway.
  • Li B; BerGenBio ASA, Bergen, Norway.
  • Fu YX; BerGenBio ASA, Bergen, Norway.
  • Minna JD; Department of Biomedicine, Centre for Cancer Biomarkers, Norwegian Centre of Excellence, University of Bergen, Bergen, Norway.
  • Brekken RA; Lyda Hill Department of Bioinformatics, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Cell Rep Med ; 3(3): 100554, 2022 03 15.
Article en En | MEDLINE | ID: mdl-35492873
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Rep Med Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas / Proteínas Tirosina Quinasas Receptoras / Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Diagnostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Rep Med Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos