Real-time assessment of individual optimal CT perfusion acquisition time in patients with ischemic stroke.
J Neuroimaging
; 32(4): 604-610, 2022 07.
Article
en En
| MEDLINE
| ID: mdl-35579598
ABSTRACT
BACKGROUND AND PURPOSE:
This study aims to investigate the feasibility of a "real-time" estimate of the optimal CT perfusion (CTP) acquisition time (Top ) in ischemic stroke patients.METHODS:
The arterial input function, the venous output function (VOF), and the time-attenuation curves of ischemic core and ischemic penumbra of 51 patients with acute ischemic stroke in anterior circulation were obtained. The curves were analyzed to determine for each patient the Top value; additionally, several time parameters were derived from each waveform. The relationship between each of these parameters and Top was investigated.RESULTS:
We found a strong linear correlation between each time parameter derived from VOF curve and Top , suggesting that the VOF waveform is rescaled from patient to patient without significant change in shape.CONCLUSIONS:
The linear correlation between Top and the VOF time to peak is well suited to implement a new technique to automatically customize the patient's CTP acquisition time. The method does not require an additional dose of contrast medium and does not increase the overall study time, so its use would be desirable to decrease the average radiation dose.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Isquemia Encefálica
/
Accidente Cerebrovascular
/
Accidente Cerebrovascular Isquémico
Límite:
Humans
Idioma:
En
Revista:
J Neuroimaging
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
/
NEUROLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Italia