Statistical methods for Mendelian models with multiple genes and cancers.

Liang, Jane W; Idos, Gregory E; Hong, Christine; Gruber, Stephen B; Parmigiani, Giovanni; Braun, Danielle

Liang, Jane W; Idos, Gregory E; Hong, Christine; Gruber, Stephen B; Parmigiani, Giovanni; Braun, Danielle.

Afiliación

Liang JW; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Idos GE; Department of Data Science, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Hong C; Center for Precision Medicine, City of Hope, Duarte, California, USA.
Gruber SB; Center for Precision Medicine, City of Hope, Duarte, California, USA.
Parmigiani G; Center for Precision Medicine, City of Hope, Duarte, California, USA.
Braun D; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Genet Epidemiol ; 46(7): 395-414, 2022 10.

Article en En | MEDLINE | ID: mdl-35583099

Asunto(s)

Predisposición Genética a la Enfermedad; Neoplasias; Teorema de Bayes; Estudios de Cohortes; Humanos; Modelos Genéticos; Neoplasias/genética

Palabras clave

Mendelian models; germline panel gene testing; pathogenic variants; precision prevention; risk prediction

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Predisposición Genética a la Enfermedad / Neoplasias Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Genet Epidemiol Asunto de la revista: EPIDEMIOLOGIA / GENETICA MEDICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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