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Adverse impact of postoperative intra-abdominal infectious complications on cancer recurrence-related survival after curative gastric cancer surgery.
Takebayashi, Katsushi; Murata, Satoshi; Kaida, Sachiko; Yamaguchi, Tsuyoshi; Otake, Reiko; Miyake, Toru; Ueki, Tomoyuki; Kojima, Masatsugu; Iida, Hiroya; Maehira, Hiromitsu; Mori, Haruki; Shimizu, Tomoharu; Tani, Masaji.
Afiliación
  • Takebayashi K; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan. Electronic address: katsushi@belle.shiga-med.ac.jp.
  • Murata S; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan; Cancer Center, Shiga University of Medical Science Hospital, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Kaida S; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Yamaguchi T; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Otake R; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Miyake T; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Ueki T; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Kojima M; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Iida H; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Maehira H; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Mori H; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Shimizu T; Medical Safety Section, Shiga University of Medical Science Hospital, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
  • Tani M; Department of Surgery, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan.
Am J Surg ; 224(3): 949-954, 2022 09.
Article en En | MEDLINE | ID: mdl-35599072
ABSTRACT

BACKGROUND:

This study aimed to evaluate the impact of postoperative intra-abdominal infectious complications (PICs) on survival after surgery for gastric cancer.

METHODS:

A total of 152 patients who underwent curative gastrectomy for gastric cancer were included. The effect of clinicopathological features and PICs on recurrence-free survival (RFS) and overall survival (OS) were investigated.

RESULTS:

The median age was 67 years. The pathological stage was stage I (61), II (40), and III (51). Thirty-two patients (21.1%) had PICs 9, pancreatic fistula; 14, anastomotic leakage; and 17, intra-abdominal abscess. The five-year RFS and OS rates were significantly lower in patients with PICs than in those without PICs (63.4 vs. 85.6%; p < 0.01 and 56.4 vs. 80.3%; p < 0.01, respectively). In multivariate analysis, intraoperative blood loss was an independent prognostic factor for PICs.

CONCLUSIONS:

Patients with PICs had worse clinical outcomes. Reducing intraoperative bleeding may improve the prognosis of gastric cancer.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Aged / Humans Idioma: En Revista: Am J Surg Año: 2022 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Aged / Humans Idioma: En Revista: Am J Surg Año: 2022 Tipo del documento: Article