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Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism.
Tapio, Joona; Halmetoja, Riikka; Dimova, Elitsa Y; Mäki, Joni M; Laitala, Anu; Walkinshaw, Gail; Myllyharju, Johanna; Serpi, Raisa; Koivunen, Peppi.
Afiliación
  • Tapio J; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Halmetoja R; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Dimova EY; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Mäki JM; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Laitala A; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Walkinshaw G; FibroGen Inc, San Francisco, California, USA.
  • Myllyharju J; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland.
  • Serpi R; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland; Faculty of Medicine, University of Oulu, Oulu, Finland; Biobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland.
  • Koivunen P; Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, Oulu Center for Cell-Matrix Research, University of Oulu, Oulu, Finland. Electronic address: peppi.koivunen@oulu.fi.
J Biol Chem ; 298(8): 102222, 2022 08.
Article en En | MEDLINE | ID: mdl-35787374
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Prolina Dioxigenasas del Factor Inducible por Hipoxia / Isoenzimas Límite: Animals Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Finlandia
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Prolina Dioxigenasas del Factor Inducible por Hipoxia / Isoenzimas Límite: Animals Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Finlandia