Osteoimmunology in periodontitis; a paradigm for Th17/IL-17 inflammatory bone loss.
Bone
; 163: 116500, 2022 10.
Article
en En
| MEDLINE
| ID: mdl-35870792
ABSTRACT
Periodontitis is a prevalent human disease of inflammation-induced bone destruction. Through studies in patient lesions of rare and common forms of periodontitis and animal model experimentation, Th17/IL-17 related immune pathways have emerged as mediators of disease pathology. In this focused review, we examine mechanisms of induction, amplification and pathogenicity of Th17 cells in periodontitis.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Periodontitis
/
Pérdida de Hueso Alveolar
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Bone
Asunto de la revista:
METABOLISMO
/
ORTOPEDIA
Año:
2022
Tipo del documento:
Article