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Two new antimicrobial monoterpenoid indole alkaloids from the roots of Rauvolfia yunnanensis.
Hao, Wu; Ma-Long, Qin; Kun, Fan; Wen, Gao; Rui-Rong, Guo; Shan-Ze, Yin; Wei-Yan, Hu; Lan-Chun, Zhang; Rong-Ping, Zhang; Hao-Fei, Yu; Yu-Peng, Li; Cai-Feng, Ding.
Afiliación
  • Hao W; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Ma-Long Q; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Kun F; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Wen G; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Rui-Rong G; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Shan-Ze Y; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Wei-Yan H; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Lan-Chun Z; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Rong-Ping Z; Yunnan Key Laboratory of Southern Medicinal Resources, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China.
  • Hao-Fei Y; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Yu-Peng L; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
  • Cai-Feng D; School of Pharmaceutical Science and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming 650031, China.
J Asian Nat Prod Res ; 25(5): 429-437, 2023 May.
Article en En | MEDLINE | ID: mdl-35930443
ABSTRACT
Two new monoterpenoid indole alkaloids 3-hydroxylochnerine (1) and 10-hydroxyvinorine (2) were isolated from the roots of Rauvolfia yunnanensis. Their structures were elucidated based on the analysis of spectroscopic data and ECD calculation. Both compounds exhibited potent antimicrobial activity against Bacillus subtilis and Escherichia coli, and their activities were comparable to the well-known antibacterial drug berberine.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rauwolfia / Alcaloides de Triptamina Secologanina / Antiinfecciosos Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Rauwolfia / Alcaloides de Triptamina Secologanina / Antiinfecciosos Idioma: En Revista: J Asian Nat Prod Res Asunto de la revista: BOTANICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China